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Dr. Raffaele Spanò has been a Technician in the Nanotechnology for Precision Medicine research line at the Istituto Italiano di Tecnologia since July 2019.

He focuses on developing Polymeric Microparticles loaded with thrombolytic drugs, such as Tissue-Type Plasminogen Activator, for therapeutic applications in vascular diseases.

He holds a Ph.D. in Tissue Engineering and Regenerative Medicine from the Università Degli Studi di Genova.

During his Ph.D., he developed a Human Platelet-Rich Plasma-based additive for cell culture and skin dressings to enhance wound healing, detailed in his thesis, "Platelet derivatives: from the Laboratory Bench to the Bedside."

Dr. Spanò also earned an MSc Degree in Applied Science, Medical, and Pharmaceutical Biotechnology from the Università Degli Studi di Genova, where his thesis, "Alteration of bone turnover and growth plate in transgenic mice overexpressing Lipocalin-2 in bone," focused on significant discoveries.

Early in his career, he contributed to groundbreaking bone and cartilage regeneration research using stem cells and blood derivatives.

Education

Title: Ph.D. in Tissue Engineering and Regenerative Medicine
Institute: Università degli Studi di Genova
Location: Genova
Country: Italy
From: 2013 To: 2016

Title: Master Degree in Applied Science, Medical and Pharmaceutical Biotechnology
Institute: Università degli Studi di Genova
Location: Genova
Country: Italy
From: 2006 To: 2011

All Publications
2022
Moore T.L., Cook A.B., Bellotti E., Palomba R., Manghnani P., Spano R., Brahmachari S., Di Francesco M., Palange A.L., Di Mascolo D., Decuzzi P.
Correction: Shape-specific microfabricated particles for biomedical applications: a review (Drug Delivery and Translational Research, (2022), 12, 8, (2019-2037), 10.1007/s13346-022-01143-4)
Drug Delivery and Translational Research, vol. 12, (no. 8)
Erratum Journal
2022
Moore T.L., Cook A.B., Belotti E., Palomba R., Manghnani P., Spano R., Brahmachari S., Di Francesco M., Palange A.L., Di Mascolo D., Decuzzi P.
Shape-specific microfabricated particles for biomedical applications: a review
Drug Delivery and Translational Research
2022
Romaldini A., Spanò R., Catalano F., Villa F., Poggi A., Sabella S.
Sub-lethal concentrations of graphene oxide trigger acute-phase response and impairment of phase-I xenobiotic metabolism in Upcyte® Hepatocytes
Frontiers in Bioengineering and Biotechnology
Article Journal
2021
Di Mascolo D., Palange A.L., Primavera R., Macchi F., Catelani T., Piccardi F., Spano R., Ferreira M., Marotta R., Armirotti A., Gallotti A.L., Galli R., Wilson C., Grant G.A., Decuzzi P.
Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours
Nature Nanotechnology, vol. 16, (no. 7), pp. 820-829
2019
Soldani G., Murzi M.b., Faita F.C., Di Lascio N.C.D., Al Kayal T.A., Spanò R., Canciani B., Losi P.
In vivo evaluation of an elastomeric small-diameter vascular graft reinforced with a highly flexible Nitinol mesh
Journal of Biomedical Materials Research - Part B Applied Biomaterials